Dataset SARS-CoV2-cytokines y2021m02 [50]

<b>Comparison of cytokines levels among COVID-19 patients living at sea level and high altitude</b> <b>ABSTRACT</b> <b>Objective:</b> The objective of this study was to compare the levels of pro-inflammatory cytokines (IL-6, IL-2, IL-10, INF-α and IFN-γ) in COVID-19 patients and healthy subjects, residing in two cities of Peru at different altitudes. <b>Results:</b> A total of 35 COVID-19 patients and 10 healthy subjects were recruited from each study site. The mean levels of IL-6 (p&lt;0.03) and TNF-α (p&lt;0.01) were significantly different among the study groups. In the case of IL-6, patients from Lima had a mean level of 16.2 pg/ml (healthy) and 48.3 pg/ml (COVID-19), meanwhile, patients from Huaraz had levels of 67.3 pg/ml (healthy) and 97.9 pg/ml (COVID-19). Regarding TNF-α, patients from Lima had a mean level of 25.9 pg/ml (healthy) and 61.6 pg/ml (COVID-19), meanwhile, patients from Huaraz had levels of 89.0 pg/ml (healthy) and 120.6 pg/ml (COVID-19). The levels of IL-2, IL-10 and IFN-γ) were not significantly different in the study groups.