Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel–Crafts Cascade Reaction of 1,3-Nitroenynes and 3‑Pyrrolyloxindoles
收藏NIAID Data Ecosystem2026-03-12 收录
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https://figshare.com/articles/dataset/Organocatalytic_Asymmetric_Synthesis_of_Aza-Spirooxindoles_via_Michael_Friedel_Crafts_Cascade_Reaction_of_1_3-Nitroenynes_and_3_Pyrrolyloxindoles/14156387
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资源简介：
An asymmetric [3+3] cyclization of
nitroenynes and 3-pyrrolyloxindoles
has been realized with a chiral bifunctional squaramide catalyst.
This Michael/Friedel–Crafts cascade strategy provides a facile
and efficient access to enantioenriched polycyclic aza-spirooxindoles
with 32–95% isolated yields and excellent stereocontrol under
mild reaction conditions.
创建时间：
2021-03-03
