Transcription profiling of rat myometrium in the transition from late pregnancy to parturition
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Transcription profiling of rat myometrium in the transition from late pregnancy to parturition
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2008-10-25
相关数据集
Comparison of the in vivo transcriptome of the myometrium to the transcriptome of myometrial explants, primary cultured myometrial cells and the hTert myometrial cell line
Circulating progesterone (P4) levels decline before the onset of parturition in most animals, but not in humans. This has led to the suggestion that there is functional withdrawal of P4 action at the
NIAID Data Ecosystem40
RNA-seq Analysis of Changes in mRNA Expression for the hTERT-HMA/B Human Myometrial Cell Line treated with all Combinations of Progesterone, Forskolin, and Interleukin-1β. RNA-seq Analysis of Changes in mRNA Expression for the hTERT-HMA/B Human Myometrial Cell Line treated with all Combinations of Progesterone, Forskolin, and Interleukin-1β
Parturition involves cellular signaling changes driven by the complex interplay between progesterone (P4), inflammation, and the cyclic adenosine monophosphate (cAMP) pathway. To characterize this int
NIAID Data Ecosystem30
Progesterone Receptor Expression Declines in the Guinea Pig Uterus during Functional Progesterone Withdrawal and in Response to Prostaglandins
Progesterone withdrawal is essential for parturition, but the mechanism of this pivotal hormonal change is unclear in women and other mammals that give birth without a pre-labor drop in maternal proge
Figshare2016-01-15 更新10
Transcriptomisc Reveals Myometrial Topologically Associated Domains linked to the Onset of Human Term Labor. Transcriptomisc Reveals Myometrial Topologically Associated Domains linked to the Onset of Human Term Labor
Changes in cell phenotype are thought to occur through the expression of groups of co-regulated genes within Topologically Associated Domains (TADs). In this paper we locate genes expressed within the
NIAID Data Ecosystem40
H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition [RNA-seq]. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition [RNA-seq]
Uncovering the causes of pregnancy complications such as preterm labor requires greater insight into how the uterus remains in a non-contractile state until term and then surmounts this state to enter
NIAID Data Ecosystem20



