bNAber

This FAIRsharing record describes: Discovery of Broadly Neutralizing Antibodies (bNAbs) has given a great boost to HIV vaccine research. Study of bNAbs capable of neutralizing a broad array of different HIV strains is important for a number of reasons: (i) structures of antigens co-crystallized with bNAbs are used as templates in HIV vaccine design; (ii) bNAbs can be effective as therapeutics; (iii) preventive use of bNAbs is a promising direction in AIDS care. The goal of bNAber is to collect, analyze, compare and present bNAbs data, thus helping researchers to create HIV vaccine.本FAIRsharing记录的描述内容如下：广谱中和抗体（Broadly Neutralizing Antibodies，bNAbs）的发现极大推动了人类免疫缺陷病毒（HIV）疫苗的研究。针对能够中和多种不同HIV毒株的广谱中和抗体开展研究具备多重重要意义：(i) 与广谱中和抗体共结晶的抗原结构可作为HIV疫苗设计的模板；(ii) 广谱中和抗体可作为治疗制剂发挥效用；(iii) 广谱中和抗体的预防性应用是艾滋病（AIDS）诊疗领域极具前景的发展方向。bNAber项目的目标是收集、分析、对比并展示广谱中和抗体相关数据，以此助力科研人员开展HIV疫苗研发工作。