首页/数据集/FLT3 activation cooperates with MLL-AF4 fusion gene to abrogate the hematopoietic specification of human ESCs

FLT3 activation cooperates with MLL-AF4 fusion gene to abrogate the hematopoietic specification of human ESCs

ChEBI2013-06-04 更新2026-07-21 收录

白血病发病机制

细胞分化调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40103 数据链接链接失效反馈

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FLT3 activation cooperates with MLL-AF4 fusion gene to abrogate the hematopoietic specification of human ESCs

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创建时间：

2013-06-04

细胞分化调控

感染免疫应答

CD25, the high affinity interleukin-2 (IL-2) receptor alpha-chain, is rapidly upregulated by antigen-specific CD8+ T cells after T cell receptor stimulation. We demonstrated that during an acute viral

NIAID Data Ecosystem100

Expression data from cultured mouse bone-marrow monocytes.

细胞分化调控

肿瘤免疫微环境

Retinoic acid signaling regulates monocyte differentiation into dendritic cells or macrophages. We used microarrays to uncover gene expression changes associated with retinoic acid exposure in mouse m

NIAID Data Ecosystem40

The Role of ARX in Human Pancreatic Endocrine Specification

胰腺内分泌

细胞分化调控

The in vitro differentiation of human embryonic stem cells (hESCs) offers a model system to explore human development. Humans with mutations in the transcription factor Aristaless Related Homeobox (AR

Figshare2016-02-22 更新20

Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells

细胞分化调控

微流控细胞培养

BackgroundAutocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine

NIAID Data Ecosystem50

Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia [ATAC-seq]

白血病发病机制

表观遗传调控

MGA (Max-gene associated) is a dual-specificity transcription factor that negatively regulates MYC-target genes to inhibit proliferation and promote differentiation. Loss-of-function mutations in MGA

NIAID Data Ecosystem30

FLT3 activation cooperates with MLL-AF4 fusion gene to abrogate the hematopoietic specification of human ESCs

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