Crystal structure of human Activated Protein C (APC) complexed with PPACK

Crystal structure of human Activated Protein C (APC) complexed with PPACK Descriptor: CALCIUM ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, ... Authors: Schmidt, A.E, Padmanabhan, K, Underwood, M.C, Bode, W, Mather, T, Bajaj, S.P. Deposit date: 2008-11-06 Release date: 2008-11-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). J.Biol.Chem., 277, 2002