five

Crystal structure of hSTING with the agonist, SHR171032

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Protein Data Bank Japan2023-10-25 更新2026-04-19 收录
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Crystal structure of hSTING with the agonist, SHR171032 Descriptor: (3S,4S)-4-(3-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazol-1-yl}propyl)-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine-8-carboxamide, CALCIUM ION, Stimulator of interferon genes protein Authors: Chowdhury, R, Miller, M. Deposit date: 2021-12-20 Release date: 2022-12-21 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.68 Å) Cite: SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis. Sci Rep, 12, 2022
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2021-12-20
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