Association of PRS with hospitalization status. PRS is constructed with PRSice using the top three loci which pass the P < 5E-8 threshold in HGI7no.

Association results in this table exclude genetic PCs as covariates from the model. While an examination of PRS without genetic PCs is significant, inclusion of genetic PCs reduces significance from P = 1.96E-48 (Table 5) to 5.25E-13. Retained signal indicates that population structure does not confound our analysis. (XLSX)