Muscle expression of SOD1G93A modulates microRNA and mRNA expression pattern associated with the myelination process in the spinal cord of transgenic mice [microarray]. Mus musculus

Expression profiling of lumbar spinal cord from MLC/SOD1G93A mice and age matched controls at 120 days of age. We used Affymetrix GeneChip Mouse Gene expression 2.0 st Array to determine differential gene expression. Overall design: Samples were collected from mice MLC/SOD1G93A and controls FVB age matched at 4 month-old. Samples were collected representing each genotype and age group for RNA extraction and hybridization on Affymetrix Microarrays.