HLA DRB1 Shared Epitope and Periodontal Disease

Data obtained from 47 healthy nonsmoking Colombians. HLA DRB1 alleles were determined , and the presence shared epitope was defined according to the Gregersen classification. Periodontal indices and diagnosis were recorded according to the Center for Disease Control and the American Academy of Periodontology (CDC-AAP) and American Academy of Periodontology and the European Federation of Periodontology (AAP-EFP) 2017 classification criteria. Furthermore, the proportions of anti-Porphyromonas gingivalis (P. gingivalis) IgG1 and IgG2 antibodies and anti-cyclic citrullinated peptide (anti-CCP) antibodies were determined.