Additional file 1: Table S1. of Context dependent regulatory patterns of the androgen receptor and androgen receptor target genes

Supernatant PSA assay. Various cell lines were stimulated with different combinations of growth factors and in several co-cultures. Represented here is a selection of these samples. Concentrations: R1881 (10 nm), FGF7 (10 ng/ml), PD98059 MAPKK inhibitor (30 mM), EGF (5 ng/ml) and co-culture with 50-75 % EPT1B8 cells. + denotes added growth factor. Mesenchymal EPT1 cells with p63KD (p63 knockdown), CDH1 or ΔNp63α are described in [14]. (XLS 46 kb)

上清液前列腺特异性抗原（PSA）检测实验。本研究中，多种细胞系经不同组合的生长因子处理，并设置了多组共培养体系。本文展示的为该系列实验中的部分样本。所用试剂及浓度如下：R1881（10 nM）、FGF7（10 ng/ml）、PD98059丝裂原活化蛋白激酶激酶（MAPKK）抑制剂（30 mM）、表皮生长因子（EGF，5 ng/ml），以及与占比50%~75%的EPT1B8细胞进行共培养。符号"+"代表添加了对应生长因子。携带p63敲低（p63 knockdown）、CDH1或ΔNp63α的间质型EPT1细胞的相关信息已在文献[14]中详述。（XLS格式，46 KB）