To gain insight into signaling downstream of SFRP2 in retinoblastoma, we used siRNA to silence SFRP2 in RB383 retinoblastoma cells and assessed the resulting gene expression changes at 24 hours and 48
We aimed to identify microRNAs which are altered upon EpCAM silencing.EpCAM is over expressed molecule in Retinoblastoma. Retinoblastoma Y 79 cell line was used as model to study the differential expr
Human Induced Pluripotent Stem Cells (hiPSC) are an established patient-specific model system where opportunities are emerging for cell-based therapies. We compared and contrasted hiPSCs derived from
Retinoblastoma Y79 cell line was treated with specific siRNA to silence EpCAM gene expression in vitro and RNA was isolated for microarray experiment to study the changes in the whole gene expression
Background: Retinoblastoma (Rb) is a malignant neoplasm arising during retinal development from mutations in the RB1 gene. Loss or inactivation of both copies of RB1 results in initiation of retinobla