A full thickness macular hole following severe preeclampsia: a case report

ABSTRACT We report a case of a young woman presenting with decreased vision in the right eye. One month earlier, she developed severe preeclampsia at 22 weeks of gestation and the pregnancy was terminated. Fundus examination revealed cotton wool spots and hard exudates in the macula bilaterally, with a yellow spot at the center of the fovea in the right eye. Optic coherence tomography showed a full thickness macular hole with elevated cystoid edges in the right eye. The patient was diagnosed with macular hole secondary to preeclampsia and followed up for spontaneous closure. One month after the first visit, surgical intervention was suggested due to declining vision. Three months later, the patient agreed to surgery. She underwent pars plana vitrectomy with a temporal inverted internal limiting membrane flap and C3F8 endotamponade, which provided anatomic and visual improvement.

摘要 本文报告1例以右眼视力下降为就诊主诉的年轻女性病例。患者于本次就诊前1个月，在妊娠22周时罹患重度子痫前期，随后终止妊娠。眼底检查显示双眼黄斑区存在棉絮样渗出斑与硬性渗出，右眼黄斑中心凹处可见黄色斑点。光学相干断层扫描（Optical Coherence Tomography）显示右眼存在全层黄斑裂孔，伴囊样边缘隆起。患者被诊断为子痫前期继发黄斑裂孔，并接受自发闭合情况的随访。首次就诊1个月后，因患者视力进行性下降，医师建议手术干预；3个月后，患者同意接受手术治疗。患者接受了经睫状体平坦部玻璃体切割联合颞侧翻转内界膜瓣术及C3F8气体眼内填塞术，术后解剖结构与视力均获得改善。