Clinical and biological characteristics of Curachik patients*.

* This trial included adult patients (18–65 years old) with a typical presentation of acute chikungunya disease (defined by acute febrile arthralgia) diagnosed within less than 48 hours. Exclusively general practitioners (GPs) enrolled the eligible patients, during the 2006 CHIKV outbreak on Reunion Island. The case definition of CHIKV positive patients relied on the association of a chikungunya-specific positive RT-PCR on D1 and seroconversion on D16 ; the case definition of CHIKV negative patients relied on the association of a chikungunya-specific negative RT-PCR on D1 and negative serology on D16. Laboratory confirmed chikungunya cases (CHIKV+, 54 patients) were compared with those excluded (CHIKV−, 22 patients).