Metastatic and aggressive renal cell carcinoma mimicking a unilateral choroidal tuberculoma

ABSTRACT Ocular metastases from systemic tumors are uncommon. The choroid is the most frequent target, with a preference for elderly individuals. Lung cancer is the predominant primary tumor that metastasizes to the eyes in males, although other ocular conditions such as uveitis and retinal lesions can mimic secondary tumor implants in ocular tissues. On fundoscopy, choroidal metastasis resembles other infectious processes, especially choroidal tuberculoma. Therefore, patients presenting with choroidal masses should undergo detailed clinical examinations, especially if the mass is the first manifestation of a systemic and severe disease. In this report, we describe a young man with a metastatic choroidal tumor secondary to papillary renal cell carcinoma mimicking a unilateral choroidal tuberculoma.

摘要：系统性肿瘤继发的眼部转移瘤较为少见。脉络膜（choroid）是最常受累的部位，好发于老年人群。男性患者中，肺癌是引发眼部转移的最主要原发肿瘤；不过葡萄膜炎（uveitis）、视网膜病变等其他眼部病症，可模拟眼部组织内的继发性肿瘤种植灶。在眼底镜检查（fundoscopy）下，脉络膜转移瘤与其他感染性病变表现相似，尤以脉络膜结核瘤（choroidal tuberculoma）为甚。因此，当患者出现脉络膜肿物时，需接受详尽的临床检查，尤其当该肿物为全身性重症疾病的首发表现时。本报告将介绍一例由乳头状肾细胞癌（papillary renal cell carcinoma）继发脉络膜转移瘤的年轻男性病例，其病灶表现疑似单侧脉络膜结核瘤。