Amino acid differences for the key functional residues of nucleoprotein (NP).

Amino acid residues corresponding to the key residues for La Cross virus NP but with significant differences (shown in bold) were listed for the nine group C viruses and other orthobunyavirus species, which include NPs for Apeu (ACZ65466), I612045 virus (AED98378), Oyo (AEE01389), Leanyer (AEA02984) and Wyeomyia (AEZ35275). Other orthobunyavirus NPs that were compared but have no differences at these residue positions include Bunyamwera, Oropouche, Sathuperi, Shamonda, Akabane, Simbu, Aino, Guaroa (CAA51847), Manzanilla (AFI24665), and Schmallenberg (CCF55031) viruses.