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Glucocorticoids Promote Breast Cancer Metastasis

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP176637
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Next Generation Sequencing was applied to investigate the heterogeneity between tumors and distant metastases in different models of Breast Cancer cell lines and primary-derived xenografts. Global transcriptional profiling of the primary tumor and matched distant metastases (lung, liver, spleen) as well as circulating tumor cells (CTCs) allowed to identify glucocorticoid signalling as a mediator of metastasis. Overall design: RNA-Seq in 4 different Breast Cancer models to investigate glucorticoid signalling role in metastasis
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2019-09-24
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