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A Basophil-Fibroblast Pro-inflammatory Axis Fuels Type 2 Skin Inflammation [scRNA-Seq]

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP560422
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To better understand cell-cell interactions driving type 2 skin inflammation, we conducted scRNA-seq on two murine models of type 2 skin inflamation, MC903 and Oxazolone (OXA), using the 10X genomics platform Overall design: MC903/OXA treated or normal ear+neck skin were harvested and pooled for each sample (n=3 mice per condition). Briefly, skin samples were digested using the Miltenyi Multi-tissue dissociation kit. Dead cells were removed using the biolegend mojosort mouse dead cell removal kit. scRNA-seq libraries were generated and analyzed in-house using the 10X genomics platform
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2026-02-07
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