Vibrio Genome sequencing

This study aimed at comprehensively analysing the genomic data of clinical and environmental V. cholerae isolates from the recent 2022-2023 cholera outbreak in Kenya. We performed whole genome sequencing for the isolates in this outbreak and compared them with historical genomes from Kenya, Uganda, Tanzania and Haiti. We generated data that provides important insights in predicting disease transmission patterns especially between bordering countries, monitoring evolution of new variants and identifying the emergence of virulent and antimicrobial resistant strains. These findings are expected to inform public health strategies for preventing, controlling and eventually eliminating cholera in Kenya.