QR GWAS summary statistics for 39 quantitative traits in the UK Biobank

Quantile regression (QR) GWAS summary statistics from the study "Genome-wide discovery for biomarkers using quantile regression at biobank scale". The preprint is available at https://doi.org/10.1101/2023.06.05.543699. 

List of traits

A comma-delimited text file, QRGWAS.Traits_n39.csv, includes the list of 39 quantitative traits from the UK Biobank reported in the QR GWAS analyses above.

Summary statistics

The tab-delimited text files are QR GWAS summary statistics, which are bgzip compressed (.tsv.gz files) and tabix indexed (.tbi files).

Column "CHR": chromosome

Column "POS": based pair position

Column "ID": variant ID

Column "REF": non-effect allele

Column "ALT": effect allele tested in GWAS

Column "EAF": frequency of the effect allele

Column "N": sample size

Column "P_QR": integrated p-value of the quantile regression (QR) model across multiple quantile levels.

Column "P_LR": p-value of the linear regression (LR) association statistic

Columns from "P_Q10" to "P_Q90": quantile-specific QR p-value for the quantile levels 0.1, 0.2, ..., 0.9 (10th, 20th, ..., 90th quantiles).