Replication Data for: Tau pathology mediates the effects of amyloid on neocortical tau propagation and neurodegeneration among non-demented individuals

Deidentified cross-sectional Baltimore Longitudinal Study of Aging (BLSA) data set that will allow for the approximate replication of the cross-sectional statistical analyses presented in the paper, \"Tau pathology mediates the effects of amyloid on neocortical tau propagation and neurodegeneration among non-demented individuals\". Because this data set includes age bands rather than continuous ages and no APOE genotype information is provided, analyses cannot be replicated exactly. Continuous age and APOE genotype data as well as longitudinal data are available from the BLSA website (https://www.blsa.nih.gov). All requests are reviewed by the BLSA Data Sharing Proposal Review Committee.

本数据集为已去标识化的巴尔的摩纵向老龄化研究（Baltimore Longitudinal Study of Aging, BLSA）横断面数据，可近似复现论文《Tau病理介导淀粉样蛋白对非痴呆个体新皮层Tau传播及神经退行性变的影响》中呈现的横断面统计分析。由于本数据集仅提供年龄分组而非连续年龄数据，且未包含载脂蛋白E（APOE）基因型信息，故无法完全复现原文中的统计分析。连续年龄、APOE基因型数据及纵向数据均可通过BLSA官方网站（https://www.blsa.nih.gov）获取。所有数据申请均需经BLSA数据共享提案审查委员会审核。