Supplementary Material for: Botulinum Toxin in the Treatment of Lingual Dystonia Induced by Speaking

Primary lingual dystonia is a rare condition, especially when it is only induced by speaking. Trihexyphenidyl failed to improve the symptoms. Several case series have demonstrated the effectiveness of botulinum toxin injection for the management of focal lingual movement disorders. Only 1 case of botulinum toxin injection for primary lingual dystonia induced by speaking has been reported, but this treatment has limited effectiveness. Our patient was treated with botulinum toxin using a superficial approach for injection into the tongue with continuing excellent results. Lingual botulinum toxin injection is a fairly simple, safe and viable treatment option for lingual dystonia induced by speaking.

原发性舌肌张力障碍（Primary lingual dystonia）是一种罕见病症，仅由言语诱发的亚型更为少见。三己芬迪（Trihexyphenidyl）无法改善此类患者的临床症状。多项病例系列研究证实，肉毒杆菌毒素注射（botulinum toxin injection）对局灶性舌运动障碍的治疗效果确切。目前仅报道过1例针对言语诱发的原发性舌肌张力障碍实施肉毒杆菌毒素注射的病例，但该治疗的疗效有限。本研究的患者采用浅表入路行舌内注射肉毒杆菌毒素，术后疗效持续优异。舌肌内肉毒杆菌毒素注射是治疗言语诱发型舌肌张力障碍的一种简便、安全且可行的治疗选择。