Transcriptional Changes in the Aging Mouse Hippocampus

We sequenced mRNA from three age groups (3months (3M), 24 months (24M) and 29 months (29M)) from the full hippocampus and compared this to microarray analysis. Young (3 months (3M)) mice were compared to aged mice (29 months (29M)), n=4本研究对3个年龄组（3月龄（3M）、24月龄（24M）及29月龄（29M））小鼠的完整海马体组织开展mRNA测序，并将测序结果与微阵列分析（microarray analysis）进行对比。其中，将3月龄（3M）的年轻小鼠与29月龄（29M）的老年小鼠进行对照比较，样本量n=4。