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Additional file 11: Table S7. of Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

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https://springernature.figshare.com/articles/dataset/Additional_file_11_Table_S7_of_Differential_gene_network_analysis_for_the_identification_of_asthma-associated_therapeutic_targets_in_allergen-specific_T-helper_memory_responses/4391918
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Transcription factor target enrichment of asthma-associated genes. We compared HDM driven responses in HDM-sensitized atopics with asthma versus HDM-sensitized atopics without asthma using differential network analysis. The resulting gene list was analysed using Enrichr showing that these asthma-associated genes were enriched with targets of STAT6 signaling. (XLS 29Â kb)

哮喘相关基因的转录因子(Transcription factor)靶标富集分析。本研究采用差异网络分析方法,对比了HDM(屋尘螨)致敏伴哮喘特应性个体与HDM致敏无哮喘特应性个体的HDM诱导应答反应。通过Enrichr工具对所得基因列表进行分析后发现,这些哮喘相关基因显著富集于STAT6信号通路的靶标范围中。(XLS格式,文件大小29 KB)
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Figshare
创建时间:
2016-12-15
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