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Crystal structure of human PCAF bromodomain in complex with compound SL1122 (compound 13)

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of human PCAF bromodomain in complex with compound SL1122 (compound 13) Descriptor: 1,2-ETHANEDIOL, Histone acetyltransferase KAT2B, ~{N}-(1,4-dimethyl-2-oxidanylidene-quinolin-7-yl)methanesulfonamide Authors: Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2015-12-16 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain. J.Med.Chem., 59, 2016
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2015-12-16
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