Age-related physiological dysregulation progresses slowly in semi-free-ranging chimpanzees

Lifestyle has widespread effects on human health and aging. Prior results from chimpanzees, one of the closest evolutionary relatives of humans, indicate that these lifestyle effects may also be shared with other species, as semi-free-ranging chimpanzees fed a naturalistic diet show healthier values in several specific health biomarkers, compared with their sedentary, captive counterparts. Here, we examined how lifestyle factors associated with different environments affect rates of physiological aging in closely related chimpanzees (Pan troglodytes). We compared physiological dysregulation, an index of biological aging, in semi-free-ranging chimpanzees in an African sanctuary versus captive chimpanzees in US laboratories. If the rate of aging is accelerated by a high-calorie diet and sedentism, we predicted greater age-related dysregulation in the laboratory populations. Conversely, if the costs of a wild lifestyle accelerate aging, then semi-free-ranging chimpanzees at the sanctuary, ..., , , # Data from: Age-related physiological dysregulation progresses slowly in semi-free-ranging chimpanzees

[https://doi.org/10.5061/dryad.37pvmcvt7](https://doi.org/10.5061/dryad.37pvmcvt7)

Study Authors: M. Cole, P. Barnes, I. Monroe, J. Rukundo, M. Emery Thompson & A.G. Rosati

Contact: [[e-mail]](mailto:[e-mail]) or [[e-mail]](mailto:[e-mail])

## Description of the data and file structure

This data set consists of three data files (.xlsx format) for the different components of the data reported in this work. For each file, there is a key tab in the file defining each variable reported in the main data tab. NAs in these files indicate no available data for that specific measure for that individual in the noted year of sampling. The specific files are:

*1. Data - Cole et al - Sanctuary Chimpanzee Biomarkers.* This file comprises the raw biomarker data from the sanctuary-living chimpanzees that were used to derive dysregulation scores from this p...