Additional file 2 of GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo

NIAID Data Ecosystem2026-03-12 收录

数据链接：

https://figshare.com/articles/dataset/Additional_file_2_of_GRK2_regulates_GLP-1R-mediated_early_phase_insulin_secretion_in_vivo/14157724 数据链接链接失效反馈

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Additional file 2. Data and results supporting the conclusions of this article.

创建时间：

2021-03-03

Age-dependent human β cell proliferation induced by GLP-1 and calcineurin signaling. Age-dependent human β cell proliferation induced by GLP-1 and calcineurin signaling

年龄依赖性β细胞增殖

GLP-1信号通路

We developed an engraftment strategy to examine age-associated human islet cell replication and found that Ex-4, an agonist of GLP-1R, stimulates human β cell proliferation in juvenile, but not adult

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Dataset for: The thermodynamic basis of glucose stimulated insulin release: a model of the core mechanism.

胰岛素分泌机制

糖尿病代谢模型

A model for glucose sensing by pancreatic β-cells is developed and compared to the available experimental data. The model brings together mathematical representations for the activities of the glucos

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Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets

胰岛β细胞振荡

胰岛素分泌机制

Pancreatic islets manage elevations in blood glucose level by secreting insulin into the bloodstream in a pulsatile manner. Pulsatile insulin secretion is governed by islet oscillations such as bursti

Figshare2016-10-28 更新10

Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/−) knockout mouse

基因敲除模型

胰岛素分泌机制

The mammalian anx7 gene codes for a Ca(2+)-activated GTPase, which supports Ca(2+)/GTP-dependent secretion events and Ca(2+) channel activities in vitro and in vivo. To test whether anx7 might be invo

PubMed Central1999-11-23 更新30

Holdemanella biformis improves glucose tolerance via GLP-1 signalling in diet-induced obese mice. Holdemanella biformis oral adminstration improves glucose tolerance

肠道微生物与糖尿病

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Impaired glucose homeostasis in obesity is ameliorated by enhancing the glucoregulatory actions of glucagon-like peptide 1 (GLP-1). Strategies that enhance the endogenous GLP-1 sensitivity and its sec

NIAID Data Ecosystem20

Additional file 2 of GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo

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