m6A and YTHDF proteins control the subcellular localization of select neuronal mRNAs

NIAID Data Ecosystem2026-03-14 收录

RNA表观遗传学

神经元RNA定位

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE194208 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2022-11-03

Analysis of m6A methylome in CHAPIR overexpressed heart [MeRIP]

RNA表观遗传学

心脏疾病分子机制

To elucidate the molecular mechanism by which cardiac-hypertrophy-associated piRNA (CHAPIR) regulates m6A modification, we performed m6A methylated RNA immunoprecipitation sequencing (MeRIP-seq) in co

NIAID Data Ecosystem20

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis. Homo sapiens

RNA表观遗传学

RNA稳定性调控

RNA modifications are integral to regulation of RNA metabolism. One such abundant mRNA modification is m6A, which impacts various aspects of RNA metabolism including splicing, transport and degradatio

NIAID Data Ecosystem10

N-acetyltransferase NAT10 Controls Cell Fates via RNA Cytidine Acetylation

RNA表观遗传学

细胞命运调控

We show that NAT10-ac4C axis significantly regulates cell fates. To identify the molecular mechanisms of NAT10-ac4C-ANP32B axis in cell-fate transitions, we construct shNAT10 and shANP32B hESCs. acRIP

NIAID Data Ecosystem00

Table_1_Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta.docx

主动脉夹层分子机制

RNA表观遗传学

Objective: To investigate the N6-methyladenosine (m6A) modification and the expressions of the m6A regulatory genes in the acute aortic dissection (AD). Methods: MeRIP-seq and RNA-seq experiments of a

NIAID Data Ecosystem10

RNA Demethylase ALKBH5 Induces Inflammation and Apoptosis in Human Retinal Endothelial Cells by Regulating SOX4 Expression in an m6A-Dependent Manner. Homo sapiens

RNA表观遗传学

视网膜色素上皮病理

We explored the downstream genes of ALKBH5 using RNA-seq in human retinal endothelial cells with stable ALKBH5 downregulation and control cells.

NIAID Data Ecosystem10