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Crystal structure of IL-17A in complex with compound 18

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Protein Data Bank Japan2024-10-09 更新2026-04-19 收录
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Crystal structure of IL-17A in complex with compound 18 Descriptor: (4~{S})-1-[(~{R})-[2-[(~{S})-[4,4-bis(fluoranyl)cyclohexyl]-[[5-[1,1-bis(fluoranyl)ethyl]-1,3,4-oxadiazol-2-yl]amino]methyl]imidazo[1,2-b]pyridazin-7-yl]-cyclopropyl-methyl]-4-(trifluoromethyl)imidazolidin-2-one, Interleukin-17A Authors: Rondeau, J.M, Lehmann, S, Scheufler, C. Deposit date: 2024-06-04 Release date: 2024-10-02 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.048 Å) Cite: Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and alpha-Fluoroacrylate Containing IL-17 Inhibitors. J.Med.Chem., 67, 2024
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2024-06-04
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