Gloreha symfonia - statistics.xlsx

Aims: The main aim of the thesis was to evaluate and compare the effectiveness of two therapeutic approaches using robot-assisted glove Gloreha Sinfonia to perform Activity of daily living in patients after acquired brain injury. Methods: The study is an empirical quantitative research, a monocentric randomized controlled, simply blinded study. The study compares two groups, group A (n = 20) used a robot-assisted Gloreha glove with a bimanual approach, group B (n = 20) had therapy with a robot-assisted Gloreha glove with an unimanual approach. All patients were evaluated for eligibility and underwent initial testing (T1). Patients in both groups had therapy (unimanual / bimanual) for three weeks (15x), retest (T2) was performed after completion of the intervention, and a follow-up evaluation was performed after 1 month (T3). Patients were always evaluated by the Upper Extremity Motor Activity Log (UE MAL), Motor Assessment Scale (MAS), Action Research Arm Test (ARAT), Box and Block test (BBT) and Motricity Index (MI). Results: According to the results of the MAS test in group A, there was a statistically significant improvement in upper limb function in category 8 at the time T2 (p = 0.038) and at the time T3 (p = 0.044) and in category 7 at the time T3 (p = 0.015). UE MAL in group A showed a marginal statistically significant improvement in UE function at the time T2 (p = 0.07) and at the time T3 (p = 0.1). There was a statistically significant increase in muscle strength according to MI at the time T2 for the shoulder (p = 0.053) and at the time T3 for the elbow (p = 0.027), a marginal significant increase in muscle strength occurred at both times (p = 0.080 and p = 0.075). Conclusion: The inclusion of bimanual robot-assisted therapy appears to be effective in restoring functional utilization of the upper limb during activities of daily living in patients after acquired brain injury with moderate to severe hemiparesis. Bimanual robot-assisted therapy also has a positive effect on the muscle strength of a whole limb研究目的：本研究旨在评估并对比两种采用机器人辅助手套Gloreha Sinfonia开展日常生活活动（Activity of daily living）训练的治疗方案，针对获得性脑损伤（Acquired Brain Injury）患者的康复有效性。 研究方法：本研究为实证定量研究，属于单中心随机对照单盲试验。研究设置两组受试者：A组（n=20）采用双侧协同模式的机器人辅助Gloreha手套康复训练，B组（n=20）采用单侧模式的机器人辅助Gloreha手套康复训练。所有受试者均通过入组资格筛查并完成初始测评（T1）；两组受试者均接受为期3周、共15次的单侧/双侧协同康复训练，干预结束后进行复测（T2），并于干预后1个月完成随访测评（T3）。测评工具包括上肢运动活动日志（Upper Extremity Motor Activity Log, UE MAL）、运动评定量表（Motor Assessment Scale, MAS）、动作研究上肢测试（Action Research Arm Test, ARAT）、箱块测试（Box and Block Test, BBT）以及运动功能指数（Motricity Index, MI）。 研究结果：A组的MAS测评结果显示，在T2时间点的第8维度（p=0.038）、T3时间点的第8维度（p=0.044）以及T3时间点的第7维度（p=0.015）中，上肢功能均出现具有统计学意义的改善。A组UE MAL测评结果显示，在T2时间点（p=0.07）及T3时间点（p=0.1）的上肢功能改善呈现边际统计学显著性。根据MI测评结果，A组在T2时间点的肩部肌力（p=0.053）、T3时间点的肘部肌力（p=0.027）均出现具有统计学意义的提升；此外在两个测评时间点均出现边际显著性的肌力提升（p=0.080及p=0.075）。 研究结论：对于伴中重度偏瘫的获得性脑损伤患者，纳入双侧协同机器人辅助疗法可有效恢复其在日常生活活动中上肢的功能使用能力。此外，双侧协同机器人辅助疗法对患肢整体肌力亦具有积极改善作用。