Synthesis of Chiral Bicyclic Guanidinium Salts using Di(imidazole-1-yl)methanimine
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https://figshare.com/articles/dataset/Synthesis_of_Chiral_Bicyclic_Guanidinium_Salts_using_Di_imidazole-1-yl_methanimine/3395014
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资源简介:
A detailed account
of the synthesis of chiral bicyclic guanidinium
salts is presented. This work represents the first systematic investigation
of an approach toward the challenging target molecules via a key guanylation
step employing di(imidazole-1-yl)methanimine (6) followed
by a two-fold cyclization, which resulted in guanidinium salts 8 and 10. Factors governing the regioselectivity
of the final cyclization step are discussed based on further data
obtained in the course of the attempted syntheses of two additional
bicyclic guanidinium salts.
创建时间:
2016-05-27



