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Synthesis of Chiral Bicyclic Guanidinium Salts using Di(imidazole-1-yl)methanimine

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Synthesis_of_Chiral_Bicyclic_Guanidinium_Salts_using_Di_imidazole-1-yl_methanimine/3395014
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资源简介:
A detailed account of the synthesis of chiral bicyclic guanidinium salts is presented. This work represents the first systematic investigation of an approach toward the challenging target molecules via a key guanylation step employing di­(imidazole-1-yl)­methanimine (6) followed by a two-fold cyclization, which resulted in guanidinium salts 8 and 10. Factors governing the regioselectivity of the final cyclization step are discussed based on further data obtained in the course of the attempted syntheses of two additional bicyclic guanidinium salts.
创建时间:
2016-05-27
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