Royal Jelly Acid in Ulcerative Colitis Treatment: Modulating miR-210-3P/Gbp3 Pathway and Pyroptosis via miRNA Expression and NLRP3 Inflammasome

This study focuses on the mRNA sequencing analysis of DSS-induced colitis in mice and examines the therapeutic effects of RJA. We conducted high-throughput mRNA sequencing to explore gene expression changes and the molecular mechanisms by which RJA mitigates colitis symptoms in DSS-treated mice. Overall design: Study Type: High-throughput sequencing of mRNA. Organism: Mus musculus (C57BL/6J mice). Total Number of Samples: 9 Groups/Conditions: Control group (normal diet and water). DSS-treated group (2.5% DSS in drinking water). RJA group (2.5% DSS in drinking water + RJA treatment). Sample Source: colon samples from mice. Specific Focus: mRNA sequencing to analyze differential gene expression in response to DSS and RJA treatment.