DNA methylation and transciptomic signatures in patients with peanut- and multi-food allergy [array]. DNA methylation and transciptomic signatures in patients with peanut- and multi-food allergy [array]

This study profiled the epigenomes and transcriptomes of total B cell populations from adolescents with peanut-only (single food allergy- SA) and multi-food allergy (MA). We found distinct epigenetic and transcriptomic differences between food allergic patients and controls, in addition to SA- and MA- group specific signatures, with Overall design: DNA methylation profiles of total B cell populations isolated using flow cytometry from single-food allergic, multi-food allergic, and non-allergic adolescents.