Crystal structure of a hydroxamate based inhibitor EN140 in complex with the MMP-9 catalytic domain
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Crystal structure of a hydroxamate based inhibitor EN140 in complex with the MMP-9 catalytic domain Descriptor: (2R)-4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxy-2-{[(4'-methoxybiphenyl-4-yl)sulfonyl](propan-2-yloxy)amino}butanamide, 1,2-ETHANEDIOL, AZIDE ION, ... Authors: Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Dive, V, Rossello, A. Deposit date: 2014-11-20 Release date: 2015-08-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity. J.Med.Chem., 58, 2015
创建时间：
2014-11-20
