Additional file 17: of Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells

KEGG pathways enriched in budesonide-repressed genes in airway epithelial cell variants and tissue. Budesonide-repressed genes ≤0.8 fold (P ≤ 0.05) in A549 (1033 genes), BEAS-2B (1687 genes), HBE (923 genes), and airway tissue (341 genes) were subjected to KEGG pathway analysis using DAVID. KEGG pathways that were significantly enriched (EASE score ≤ 0.1) with each list and represented by at least 5 genes are listed. The terms that were significantly enriched following family-wide false discovery rate correction (Benjamini ≤0.05) are colored red. (XLSX 30 kb)

本数据集为气道上皮细胞系及组织中布地奈德抑制基因所富集的京都基因与基因组百科全书（KEGG）通路。对在A549、BEAS-2B、HBE细胞系及气道组织中表达量下调至对照的0.8倍以下（P≤0.05）的布地奈德抑制基因（其中A549含1033个基因、BEAS-2B含1687个基因、HBE含923个基因、气道组织含341个基因），采用DAVID工具开展KEGG通路富集分析。将各基因列表中EASE评分≤0.1、且覆盖至少5个对应基因的显著富集KEGG通路进行列示。经家族性错误发现率校正（Benjamini≤0.05）后仍显著富集的通路术语将以红色标注。（XLSX格式，30 KB）