Identification off-target mutations following genetic modification by CRISPR/Cas9 in Plasmodium berghei
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https://www.ncbi.nlm.nih.gov/sra/DRP007048
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资源简介:
We developed the novel CRISPR/Cas9 system in the rodent malaria parasites Plasmodium berghei. We conducted a genome-wide sequence analysis of the parental line pbcas9 and the mutant parasites after the genetic modification of non-essential gene (imc1i) to investigate whether the off-target mutation was introduced.
创建时间:
2021-03-20



