Reductive stress leads to aggregation of peripheral ER strands.
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A. Sec63-GFP images (inverted greyscale) of cells treated with DTT for the indicated time periods. Images correspond to maximal intensity projections of z-stacks processed with an ‘unsharp’ filter. In the 45 min GFP image, green arrowheads indicate aggregates of ER strands and magenta arrows indicate nuclei, whose NEs, unlike peripheral ER strands, appear unaltered. All images are shown at the same magnification. Bars, 5 µm. B. Examples of ring-shaped ER aggregates in cells treated with DTT for 130 min.
创建时间：
2016-02-24
