IgM repertoire in dark spots in skeletal muscle of Atlantic salmon

Focal dark spots (DS) in farmed Atlantic salmon fillets contain a significant number of B cells as revealed by the high abundance of immunoglobulin (Ig) transcripts in transcriptome data. The immune response in DS remains unknown while they represent a major problem in commercial aquaculture. The project characterized the diversity and clonal composition of B cells in DS, their differentiation and traffic between salmon organs and tissues.