Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.

In silico models for membrane permeability have been based on values measured for single pH. Depending on the diet (fasted/fed state) and part of human intestinal the range of pH varies approximately from 2.4 to 8.0. This motivated to study and model membrane permeability of chemicals considering range of pH in the human intestinal. For this effective membrane ...