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<i>N</i>-Heterocyclic Carbene-Catalyzed Cross-Coupling of Aldehydes with Arylsulfonyl Indoles

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NIAID Data Ecosystem2026-03-06 收录
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3-(1-Arylsulfonylalkyl)indoles as electrophiles in the N-heterocyclic carbene-catalyzed umpolung reaction of aldehydes were realized for the first time. This intermolecular Stetter-type reaction features the commercially available catalyst and mild reaction conditions, providing α-(3-indolyl) ketone derivatives in high yields for a wide range of substrates.

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2016-02-26
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