Synthesis of Quinolones by Nickel-Catalyzed Cycloaddition via Elimination of Nitrile
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Substituted quinolones were efficiently synthesized via the nickel-catalyzed cycloaddition of o-cyanophenylbenzamide derivatives with alkynes. The reaction involves elimination of a nitrile group by cleavage of the two independent aryl–cyano and aryl–carbonyl C–C bonds of the amides.
创建时间：
2016-02-19
