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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase Authors: Antonysamy, s.s. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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2008-03-12
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