The Nold Laboratory – translational immunology in neonatal diseases and beyond

The collection comprises data obtained from cell culture and animal experiments as well as from human tissue by a wide spectrum of methods and technologies, including molecular biology (RNA, DNA and protein analysis, including RNA and protein arrays and flow cytometry), imaging (synchrotron, conventional and confocal microscopy, macroscopic imaging) and data mining (statistical analysis of pro- and retrospective data from humans). The data are centred around mediators of inflammation and their signalling pathways with a focus on clinically relevant topics, particularly in neonatology, with a clear translational potential本数据集涵盖通过多种实验技术与方法获取的细胞培养、动物实验及人体组织相关数据，所采用的技术手段包括分子生物学（molecular biology）相关分析（涵盖RNA、DNA与蛋白质分析，其中包含RNA芯片、蛋白质芯片及流式细胞术（flow cytometry））、成像技术（同步辐射成像、普通光学显微镜、共聚焦显微镜（confocal microscopy）与宏观成像），以及数据挖掘技术（针对人类前瞻性与回顾性数据的统计分析）。本数据集以炎症介质及其信号通路为核心研究对象，聚焦临床相关主题，尤其侧重于新生儿科（neonatology）领域，具备明确的转化研究潜力。