Expression profile of Urothelial carcinoma of the urinary bladder (UCB) or bladder cancer from Blood

The main aim of this study was to assess the changes in blood gene expression in UCB patients and to identify genes serving as biomarkers for UCB diagnosis and progression. Our study characterized the comprehensive expression profile of UCB and highlighted differences in expression patterns between UCB and healthy control The prediction of classes of bladder tumors using a limited set of genes could help in development of a clinical decision model. The main objective of the current study is to predict bladder cancer disease course by identifying markers that will predict the likelihood of progression in patients with high grade tumors. By utilizing gene expression profiling, we identified different genes as a signature biomarkers for UCB and tumor progression in risk and prognostics groups using a multiple group comparison.