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The role and function of YAP in cancer-associated fibroblasts

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE208058
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To investigate how YAP activity contributes to the functional properties of cancer-associated fibroblasts (CAFs), we established YAP-deficient cancer-associated fibroblast cell line, in which YAP expression can be inducibly silenced using shRNA, for RNA-Seq compared to wildtype CAFs. Total RNA was extracted from both wildtype CAFs and YAP-deficient CAFs for RNA-Seq. RNA-Seq data were analyzed using DESeq2 on the AIR platform (https://transcriptomics.sequentiabiotech.com/).
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2024-05-02
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