Introduction: Dementia represents a global public health challenge, and no conclusive evidence exists on how to prevent its onset or at least reduce the risk. This umbrella review aims to identify int
*Geriatric Depression Scale data were missing for 48 subjects.SD = standard deviation; ADL = Activities of Daily Living; IQR = interquartile range; MMSE = Mini-Mental State Examination.
Introduction: Dementia represents a global public health challenge, and no conclusive evidence exists on how to prevent its onset or at least reduce the risk. This umbrella review aims to identify int
After identification of lead compound 6, 5-amino-1,4-oxazine BACE1 inhibitors were optimized in order to improve potency, brain penetration, and metabolic stability. Insertion of a methyl and a triflu
