Influence of glial biotin availability on coping up with ER stress
收藏Mendeley Data2020-03-08 更新2026-04-09 收录
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We hypothesize that biotin favors BCAA utilization and its deficiency accumulates BCAA to prolong autophagy inhibition and ER stress by chronic activation of mTORC1. Ganesan, D, Ramaian Santhaseela, A, Rajasekaran, S, Selvam, S, Jayavelu, T. Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA‐mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain. J. Neurochem. 2020; 00: 1– 14. https://doi.org/10.1111/jnc.14979
创建时间：
2020-03-08
