Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin
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Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin Descriptor: GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ... Authors: Boriack-Sjodin, P.A. Deposit date: 2014-12-06 Release date: 2015-04-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.35 Å) Cite: A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat.Chem.Biol., 11, 2015
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2014-12-06
