Impact of Cugbp1 knockout on skeletal muscle and brain trancsriptome in neonatal mice. Mus musculus

To elucidate the role of Cugbp1 knockout on the structure and function of skeletal muscle and brain, we have performed a microarray of mRNA obtained from skeletal muscle and brain samples obtained from neonatal WT and Cugbp1 KO mice. Between-genotype differences were assessed using a Student's T-test, with a p-value cutoff of 0.05 and fold change cutoff of 1.5. 929 genes were identified as differentially regulated; ontological enrichments within this geneset indicated Cugbp1 may regulate differentiation, extracellulat matrix and other muscle functions during myogenesis. Overall design: The impact of Cugbp1 knockout on the skeletal muscle and brain transcriptome was assessed through a microarray of mRNA obtained from skeletal muscle and brain samples in WT and Cugbp1 KO neonatal mice. The submitter states that raw data are not available for this series.