首页/数据集/Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478)

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478)

NIAID Data Ecosystem2026-05-01 收录

寄生虫病药物研发

抑制剂复合物

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资源简介：

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478)

应用场景：

创建时间：

2023-09-20

结构生物学

抑制剂复合物

Human orotidyl-5'-monophosphate decarboxylase in complex with 6-mercapto-UMP Descriptor: 6-sulfanyluridine-5'-phosphate, Uridine 5'-monophosphate synthase Authors: Heinrich, D, Wittmann, J, Diederichs

Protein Data Bank Japan2024-03-20 更新40

ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5.6

蛋白质结构解析

抑制剂复合物

ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5.6 Descriptor: ACETIC ACID, CITRIC ACID, L-asparaginase 2 Authors: Lubkowski, J, Wlodawer, A. Deposit date: 2019-02-08 Release date: 2019-08-07

Protein Data Bank Japan2024-10-23 更新30

Synthesis, Biological Evaluation, Structure–Activity Relationship, and Mechanism of Action Studies of Quinoline–Metronidazole Derivatives Against Experimental Visceral Leishmaniasis

寄生虫病药物研发

抗利什曼药物研究

In our efforts to identify novel chemical scaffolds for the development of antileishmanial agents, a series of quinoline–metronidazole hybrid compounds was synthesized and tested against the murine mo

Figshare2019-05-24 更新00

X-ray structure of furin in complex with the dichlorophenylpyridine-based inhibitor 3

结构生物学

抑制剂复合物

X-ray structure of furin in complex with the dichlorophenylpyridine-based inhibitor 3 Descriptor: 3-[4-[5-[4-[[4-(acetamidomethyl)piperidin-1-ium-1-yl]methyl]-6-[3,5-bis(chloranyl)phenyl]pyridin-2-yl]

Protein Data Bank Japan2024-11-06 更新30

High-resolution crystal structure Streptococcus pyogenes beta-NAD+ glycohydrolase in complex with its endogenous inhibitor IFS reveals a water-rich interface

蛋白质晶体学

抑制剂复合物

High-resolution crystal structure Streptococcus pyogenes beta-NAD+ glycohydrolase in complex with its endogenous inhibitor IFS reveals a water-rich interface Descriptor: Nicotine adenine dinucleotide

Protein Data Bank Japan2024-03-20 更新30

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478)

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